教育和工作经历

2006年3月至今，电分析化学国家重点实验室，研究员、博士生导师

2002年－2006年3月, 英国利物浦大学（University of Liverpool），博士后

2001年－2002年, 英国东安格利亚大学（University of East Anglia），博士后

1997－2000年, 中科院长春应化所获得博士学位

1994－1997年, 中科院长春应化所获得硕士学位

1990－1994年, 吉林大学化学系 获得学士学位。

研究资助

国家自然科学基金面上项目和科学仪器研制专项、国家科技部重点基础研究发展计划、科技部‘973’、中国科学院科研装备研制项目

研究兴趣

纳米探针的合成与应用；生物分析与生物分子间相互作用；高通量分析；多模态成像。 

代表性研究成果介绍

1.新型微阵列生物芯片的构建与应用

基于不同基底的多肽芯片用于酶功能的研究和抑制剂筛选

纸基微阵列芯片用于激酶活性和抑制剂的研究

2.功能化纳米粒子在多模态活体成像中的应用

利用凝集素微阵列芯片筛选针对CRC的特异性凝集素，进一步结合上转换纳米粒子用于活体多模态成像

大规模制备具有肾清除性质的配位聚合物纳米点用于癌症诊疗研究

利用胰蛋白胨作为一种通用的相转移试剂来制备肾清除的纳米点用于生物成像

主要代表性论文 
1. Uncovering the Binding Specificities of Lectins with Cells for Precision Colorectal Cancer Diagnosis Based on Multimodal Imaging, Rongrong Tian, Hua Zhang, Hongda Chen, Guifeng Liu*, Zhenxin Wang*, Adv. Sci. 2018, 1800214.
2. Gram-scale synthesis of coordination polymer nanodots with renal clearance properties for cancer theranostic applications, Fuyao Liu, Xiuxia He, Hongda Chen, Junping Zhang, Huimao Zhang*, Zhenxin Wang*, Nat. Commun. 2015, 6, 8003.
3. Carbon nanofibers by pyrolysis of self-assembled perylene diimide derivative gels as supercapacitor electrode materials, Xia Liu, Aled Roberts, Adham Ahmed, Zhenxin Wang*, Xu Li, Haifei Zhang*, J. Mater. Chem. A, 2015, 3(30), 15513-15522.
4. Employing Tryptone as a General Phase Transfer Agent to Produce Renal Clearable Nanodots for Bioimaging, Fuyao Liu, Xiuxia He, Junping Zhang, Huimao Zhang*, Zhenxin Wang*, Small 2015, 11(30), 3676-3685.
5. Peptide Microarray-Based Metal Enhanced Fluorescence Assay for Multiple Profiling of Matrix Metalloproteinases Activities, Zhen Lei, Hua Zhang, Yaoqi Wang, Xianying Meng*, Zhenxin Wang*, Anal. Chem. 2017, 89, 6749-6757.
6. Sensitive Detection of Polynucleotide Kinase Activity by Paper-Based Fluorescence Assay with lambda Exonuclease Assistance, Hua Zhang, Zhen Zhao, Zhen Lei, Zhenxin Wang*, Anal. Chem. 2016, 88, 11358-11363.
7. Evaluation of Matrix Metalloproteinase Inhibition by Peptide Microarray-Based Fluorescence Assay on Polymer Brush Substrate and in Vivo Assessment, Zhen Lei, Hongda Chen, Hua Zhang, Yaoqi Wang, Xianying Meng*, Zhenxin Wang*, ACS Appl. Mater. Interfaces 2017, 9, 44241-44250.
8. Development of Sphere-Polymer Brush Hierarchical Nanostructure Substrates for Fabricating Microarrays with High Performance, Xia Liu, Rongrong Tian, Dianjun Liu, Zhenxin Wang*, ACS Appl. Mater. Interfaces 2017, 9, 38101-38108.
9. Surfactant-Free Aqueous Synthesis of Novel Ba2GdF7:Yb3+,Er3+@PEG Upconversion Nanoparticles for in Vivo Trimodality Imaging, Yang Feng, Hongda Chen, Lina Ma, Baiqi Shao, Shuang Zhao, Zhenxin Wang*, Hongpeng You*, ACS Appl. Mater. Interfaces 2017, 9, 15096-15102.
10. Poly(glycidyl methacrylate-co-2-hydroxyethyl methacrylate) Brushes as Peptide/Protein Microarray Substrate for Improving Protein Binding and Functionality, Zhen Lei, Jiaxue Gao, Xia Liu, Dianjun Liu, Zhenxin Wang*, ACS Appl. Mater. Interfaces 2016, 8, 10174-10182.
11. A novel upconversion@polydopamine core@shell nanoparticle based aptameric biosensor for biosensing and imaging of cytochrome c inside living cells, Lina Ma, Fuyao Liu, Zhen Lei, Zhenxin Wang*, Biosens. Bioelectron. 2017, 87, 638-645.
12. Polyacrylamide-phytic acid-polydopamine conducting porous hydrogel for rapid detection and removal of copper (ii) ions, Zhen Zhao, Hongda Chen, Hua Zhang, Lina Ma*, ZhenxinWang*, Biosens. Bioelectron. 2017, 91, 306-312.

研究组人员概况

副研究员：马立娜，张婳
助理研究员：陈宏达，苏敏
研究实习员：邬东阳
在读博士生：赵珍， Girma，高嘉雪，田荣荣，孙艳红，Murad
在读硕士生：简明红，徐凤琴
联合培养硕士：刘琳